Skip to main content
. 2011 Jun 2;6(6):e20301. doi: 10.1371/journal.pone.0020301

Figure 1. In vivo inhibition of neointimal formation after 6 weeks of treatment with EGb761.

Figure 1

A. H&E stained sections of the three groups. B. Intima to media ratios (IMRs) in the three groups (n = 10 in each group). Treatment with EGb761 produced a lower IMR than controls in a dose-dependent manner (the lower IMR with the higher dose of EGb761, p<0.05). C. Representative examples of aortas from ApoE-/- mice stained en-face with Oil-Red. Red color indicates the aortic arch where plaque accumulation is the highest. D. Quantification of aortic arch plaque in the three groups expressed as the mean±SEM percent. A dose-dependent decreased plaque volume was found in the EGb groups.