Table 1.

Effects of NSAIDs and other analgesics on treatment response to citalopram in humans

	Remission	No Remission	remission rate (%)	P value
NSAID	182	227	44.5	P = 0.0002
No NSAID	628	509	55.2
Analgesic	52	88	37.1	P = 0.0002
No analgesic	758	648	53.9
Both (NSAID and analgesic)	23	40	36.5	P = 0.0138
None	787	696	53.1
Either (NSAID or analgesic)	211	275	43.4	P < 0.0001
None	599	461	56.5
Vitamins	44	31	58.7	P = 0.2874
No vitamins	766	705	52.1

Number of patients in remission or not in remission at the end of 12 wk of treatment with citalopram shown as a function of presence or absence of various concomitant treatments. Data were analyzed using Fisher's exact test; P < 0.05 indicated a statistically significant relationship between the concomitant medication and the treatment outcome.