Fig. 5.

GATA1 occupancy is a major determinant for Brd3 occupancy genome-wide. The distributions of levels of Brd3 occupancy as determined by genome-wide ChIP in cells with or without active GATA1 are shown as box plots. Black bars denote the median number of normalized read counts, and boxes denote interquartile ranges (IQR). Whiskers demarcate the range of values excluding outliers as conventionally defined by > 1.5 × IQR. Statistical significance of difference was estimated by applying the Mann–Whitney U test on a random subset of data points (n = 400). “ns” indicates not significant; * indicates p < 0.05; ** indicates p < 10^-5; *** indicates p < 10^-10.