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. Author manuscript; available in PMC: 2012 Nov 15.
Published in final edited form as: Spine (Phila Pa 1976). 2011 Nov 15;36(24):E1555–E1561. doi: 10.1097/BRS.0b013e318210eec4

Figure 2. Gdf-5 deficient (bp) animals contain a reproducible and highly penetrant limb phenotype.

Figure 2

Gdf-5 heterozygous and null adult limbs are shown. A. Skeletal preparations of Gdf-5 adults demonstrating the presence of a smaller autopod in the mutant. B. Shhcre and R26R alleles permit the fate-mapping of cells that expressed Shh.