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. Author manuscript; available in PMC: 2012 Nov 15.
Published in final edited form as: Spine (Phila Pa 1976). 2011 Nov 15;36(24):E1555–E1561. doi: 10.1097/BRS.0b013e318210eec4

Figure 3. Fatemap of notochord cells in P0 (newborn) Gdf-5 heterozygous and null animals.

Figure 3

Total magnification: 100×. Newborn Gdf-5 animals containing R26R and Shhcre alleles demonstrated that notochord cells were correctly localized to the nucleus pulposus. Both control and mutant mice contained notochordal remnants (black arrows). A. Gdf-5 heterozygote. B: Gdf-5 mutant. Lower panels: H&E-stain of newborn discs.