Table 3.
Association of GR gene polymorphism (Bcl1, C>G) with clinical parameters in obese subjects (n = 198)
| Clinical features | GR gene polymorphism (Bcl1, C>G) | P-value | |
|---|---|---|---|
| G allele carrier (n = 110) | G allele non-carrier (n = 88) | ||
| Waist to hip ratio and blood pressure | |||
| WHR | 0.95 ± 0.06 | 0.93 ± 0.07 | 0.004 |
| SBP (mmHg) | 126.97 ± 7.33 | 114.16 ± 5.46 | 0.002 |
| DBP (mmHg) | 89.97 ± 8.12 | 82.36 ± 5.52 | 0.007 |
| Lipid profile | |||
| LDL-cholesterol (mg/dl) | 153.40 ± 8.04 | 154.40 ± 6.14 | 0.876 |
| VLDL-cholesterol (mg/dl) | 26.44 ± 5.40 | 25.53 ± 7.82 | 0.677 |
| HDL-cholesterol (mg/dl) | 34.34 ± 5.08 | 35.45 ± 3.43 | 0.123 |
| Triglyceride (mg/dl) | 134.23 ± 12.50 | 133.76 ± 14.09 | 0.758 |
| Total-cholesterol (mg/dl) | 216.33 ± 13.45 | 215.51 ± 14.22 | 0.324 |
| Hormonal profile | |||
| Leptin (mg/ml) | 21.11 ± 5.65 | 20.34 ± 6.45 | 0.231 |
| Insulin (μU/ml) | 23.94 ± 5.05 | 19.11 ± 4.31 | 0.046 |
| Blood glucose (mg/dl) | 123.23 ± 7.12 | 115.12 ± 8.75 | 0.044 |