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Cross-linking CD40 to CD46 inhibits CD40-mediated IgE synthesis. (A) B cells were stimulated as indicated with IL-4 and anti-CD40 mAb in the absence or presence of mAb to CD46 or CD21 and GAMIG. (B) Proliferation was measured at 4 days. Results are expressed as mean ± SD of four experiments. *P < 0.05.
