TABLE 8.
LFER Values for Pig Skin Diffusion Cells (PSFT) Logkp (n = 384)—Potts and Guy (1992) Model
| r2 | Adj. r2 | qLOO2 | q1.25%2 | qEXT2 | s | F | i | m | MF | a × logKow | b × MW |
| 0.33 | 0.33 | 0.32 | 0.32 | NA | 0.51 | 94 | 1.13(0.13) | No MF | −0.10(0.02) | −0.0058(0.0006) | |
| p < 0.001 | No MF | p < 0.001 | p < 0.001 | ||||||||
| 0.55 | 0.54 | 0.54 | 0.54 | NA | 0.35 | 152 | 2.89(0.17) | −1.23(0.09) × HBAcc | −0.10(0.02) | −0.0058(0.0005) | |
| p < 0.001 | p < 0.001 | p < 0.001 | p < 0.001 | ||||||||
Note. SE in parentheses. HBAcc, number of hydrogen bond acceptors (calculated by www.molinspiration.com); 1/MP, inverse of the melting point (literature values from Syracuse University PhysProp Database http://esc.syrres.com/interkow/physdemo.htm). NA, not applicable.