Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Jun 1;7(6):691–699. doi: 10.7150/ijbs.7.691

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

PMC Copyright notice

Fig 4 — Electrophoretic mobility shift assay of the binding of various HMGB1 proteins to cisplatin-damaged DNA. Panel A. Interaction of wild-type tailless (∆C) protein (lanes 2 and 3), in vitro acetylated ∆C at K2 (lane 4), ∆CK2/A2 mutant (lane 5), acetylated ∆CK2/A2 mutant (lane 6), ∆C K81/A81 mutant (lane 7), acetylated ∆CK81/A81 mutant (lane 8), ∆ K2/A2,K81/A81 double mutant (lane 9) and acetylated ∆CK2/A2K81/A81 mutant (lane 10). Lane 1 shows the position of free DNA. Panel B. Interaction of full-length HMGB1 (lane 2) and HMGB1K2/A2 and HMGB1K81/A81 mutants (lanes 3 and 4 respectively) with cis-platinated DNA. Lane 1 shows the position of free DNA.