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GO-203 treatment decreases Bcr-Abl levels and induces cell cycle arrest. (A-D) KU812 (A, C) and K562 (B, D) cells were treated with 5 µM GO-203 or 5 µM CP-2 each day for 2 days. The GO-203–treated cells were also incubated in the presence of 5 mM NAC. (A and B) Lysates were immunoblotted with the indicated antibodies. (C and D) Cells were fixed and analyzed for cell cycle distribution by flow cytometry.
