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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Helicobacter. 2011 Jun;16(3):169–178. doi: 10.1111/j.1523-5378.2011.00839.x

Figure 3. Protective immunity against H. pylori in IL-17AR KO mice.

Figure 3

WT and IL-17AR KO mice received intranasal immunizations once a week for four weeks with 100 µg of H. pylori sonicate plus 5 µg of cholera toxin and received an orogastric challenge of 1–2 × 107 cfu H. pylori on days 7 and 8 following this treatment. Naive and unimmunized/challenged (U/C) mice received mock immunizations of intranasal PBS. U/C mice were infected at the same time as the I/C mice. Gastric biopsies were harvested from all mice two weeks post-challenge and evaluated for gastritis (A), H. pylori load (B) and gastric neutrophil numbers (C). n = 3 – 6 mice/group. N.S. = not significant.