Table 1.
Drug groups included in the analysis, branded manufacturers between brackets and patent expiry dates
| Drug name | Branded drug | Patent expiry datea |
|---|---|---|
| ACE Inhibitors | ||
| Enalapril | Renitec® [MSD] | 13-12-1999 |
| Lisinopril | Zestril® [AstraZeneca] | 8-10-2002 |
| Ramipril | Tritace® [Sanofi-Aventis] | 13-1-2004 |
| Quinapril | Acupril® [Pfizer] | 5-10-2004 |
| Fosinopril | Newace® [BMS] | 4-7-2005 |
| Antidepressants | ||
| Fluoxetine | Prozac® [Eli Lilly] | 14-12-1999 |
| Paroxetine | Seroxat® [GSK] | 12-7-2001 |
| Citalopram | Cipramil® [Lundbeck] | 1-2-2002 |
| Moclobemide | Aurorix® [Roche] | 4-4-2002 |
| Mirtrazapine | Remeron® [Shering-Plough] | 13-9-2004 |
| Sertraline | Zoloft® [Pfizer] | 28-10-2005 |
| PPIs | ||
| Omperazol | Losec® [AstraZeneca] | 18-4-2002 |
| Lansoprazol | Prezal® [Sanofi-Aventis] | 19-12-2005 |
| Statins | ||
| Simvastatine | Zocor® [MSD] | 1-5-2003 |
| Pravastatine | Selektine® [BMS] | 2-8-2004 |
a Defined as the date of the first prescription encountered in IADB.nl