Table 5.
Predicted mean1 relative concentrations of testosterone and oestradiol in men by tertiles of right and left 2D:4D and Δr-l.
| Right Hand | Left Hand | Δr-l | ||||||||||||||
| 2D:4D tertile | mean | (95% CI) | P2trend | ρ3 | P4 | mean | (95% CI) | P2trend | ρ3 | P4 | mean | (95% CI) | P2trend | ρ3 | P4 | |
| Testosterone:oestradiol | I | 160.2 | (152.6 - 167.9) | 0.03 | -0.06 | 0.03 | 158.9 | (151.3 - 166.5) | 0.19 | -0.05 | 0.07 | 155.7 | (148.1 - 163.4) | 0.82 | -0.01 | 0.69 |
| II | 154.1 | (146.5 - 161.8) | 153.4 | (145.9 - 160.9) | 154.0 | (146.4 - 161.7) | ||||||||||
| III | 152.1 | (144.5 - 159.8) | 154.2 | (146.6 - 161.7) | 156.5 | (148.9 - 164.2) | ||||||||||
| Free testosterone:free oestradiol | I | 157.0 | (148.6 - 165.4) | 0.02 | -0.07 | 0.02 | 155.4 | (147.1 - 163.8) | 0.11 | -0.06 | 0.04 | 151.1 | (142.6 - 159.5) | 0.92 | -0.01 | 0.64 |
| II | 148.5 | (140.1 - 156.9) | 147.4 | (139.0 - 155.7) | 148.3 | (139.9 - 156.8) | ||||||||||
| III | 146.2 | (137.8 - 154.6) | 148.1 | (139.7 - 156.4) | 151.5 | (143.0 - 160.0) | ||||||||||
1Estimates from linear mixed models of the ratio of hormone concentrations on 2D:4D tertiles with laboratory batch entered as a random intercept, adjusted for ethnicity, age at blood draw, BMI, and smoking status.
2From likelihood ratio test for linear trend across 2D:4D tertiles.
3Standardised regression coefficients (correlations) from linear mixed models of the logarithm of hormone concentration on continuous 2D:4D with laboratory batch entered as a random intercept, adjusted for ethnicity, age at blood draw, BMI, and smoking status.
4From likelihood ratio test of ρ.