. 2011 May 9;38(5):2731–2741. doi: 10.1118/1.3575416

Table 2.

Clinical organ constraints to be implemented by ROCO for lung plans. The lung mean dose constraint is a proxy for NTCP ≤25% (see text); the esophagus constraint is not enforced clinically by the planner if it cannot be met without compromising coverage. Not shown in the table are nonspecific normal tissue maximum dose constraints: major hot spots (>110%) outside the PTV are not tolerated, and if the dose distribution is insufficiently conformal more than ~0.5 cm beyond the PTV, then the plan will be rejected by the treatment planner.

Structure	PTV	Lungs	Esophagus	Spinal cord	Brachial plexus
Constraint	D_max<110%	D_mean<20 Gy	D_mean<34 Gy	D_max<50 Gy	D_max<65 Gy, D₀₅<60 Gy