Table 5.

Median differences between ROCO plans and plans produced by treatment planners. D* is a target or organ dose normalized by the prescription dose (for PTVs) or clinical constraints (for organs); see text. Positive values of D* indicate either improved dose homogeneity in the PTVs, or better sparing of the OARs in ROCO plans, when compared to the treatment planner’s plans. Significance was evaluated with the Wilcoxon signed-rank test; for ROCO, the median difference in doses to targets and organs was not significantly different from the treatment planner’s.

Structure	Median D*(%)	P < 0.1?
PTV Dmax	−0.9	No
PTV Dmin	0.2	No
Lung $\stackrel{-}{D}$	−0.9	No
Cord Dmax	−1.5	No
Esophagus $\stackrel{-}{D}$	0.0	No