Table 1. Safety evaluation of oHSV after intracerebral inoculation in A/J mice.
Dose [pfu] | Virus |
|||
---|---|---|---|---|
Strain F (wild-type) |
R7041 | FΔ6 | MG18L | |
4×106 | NT | 1/10 | 6/6 | 8/8 |
2.5×106 | NT | NT | NT | 3/3 |
4×105 | NT | 3/6 | NT | NT |
4×104 | NT | 6/6 | NT | NT |
4×103 | 0/3 | NT | NT | NT |
4×102 | 0/3 | NT | NT | NT |