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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Clin Cancer Res. 2011 Apr 19;17(11):3686–3696. doi: 10.1158/1078-0432.CCR-10-3142

Table 1. Safety evaluation of oHSV after intracerebral inoculation in A/J mice.

Mice were observed for 28 days and the number of survivors / total indicated. NT, not tested

Dose [pfu] Virus
Strain F
(wild-type)
R7041 FΔ6 MG18L

4×106 NT 1/10 6/6 8/8
2.5×106 NT NT NT 3/3
4×105 NT 3/6 NT NT
4×104 NT 6/6 NT NT
4×103 0/3 NT NT NT
4×102 0/3 NT NT NT