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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Cancer Prev Res (Phila). 2011 Mar 16;4(6):897–906. doi: 10.1158/1940-6207.CAPR-10-0323

Fig. 5.

Fig. 5

Immunoblotting for survivin using PC-3 (A) and LNCaP cells (C) transiently transfected with a control nonspecific siRNA or a survivin-targeted siRNA and treated with DMSO (control) or 40 μmol/L DATS for 24 hours. Histone-associated DNA fragment release into the cytosol (a measure of apoptotic cell death) in PC-3 (B) and LNCaP cells (D) transiently transfected with a nonspecific siRNA or a survivin-targeted siRNA and treated with DMSO (control) or 40 μmol/L DATS for 24 hours. Columns, mean (n= 3); bars, SD. Significantly different (P < 0.05) compared with nonspecific siRNA-transfected cells treated with DMSO (a) and nonspecific siRNA-transfected cells treated with DATS (b) by one-way ANOVA followed by Bonferroni's multiple comparison test. Results were consistent in two independent experiments, and representative data from one such experiment are shown.