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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Cancer Prev Res (Phila). 2011 Mar 16;4(6):879–889. doi: 10.1158/1940-6207.CAPR-11-0025

Figure 4.

Figure 4

Panel A: Dose-dependent cytotoxicity induced by RLIP76-antisense (R508) in neuroblastoma cells. Cells were treated with R508 using Maxfect transfection reagent (Molecula, Inc.). Cell survival was measured by MTT cytotoxicity-assay 48 h after treatment. The values are presented as mean ± SD from two separate determinations with eight replicates each (n = 16). Panel B: cytotoxic interactions of anti-RLIP76 IgG and CDDP. Cytotoxic effects were calculated for absorbance values obtained from MTT cytotoxicity-assays. Cells were treated alone or in combinations with anti-RLIP76 IgG (10 μg/mL) and CDDP (1 μmol/L) for 48 h before MTT assay. Eight replicates were done in three separate experiments (n = 24), *p < 0.01.