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. Author manuscript; available in PMC: 2011 Jun 4.
Published in final edited form as: Nat Rev Endocrinol. 2009 Nov;5(11):611–619. doi: 10.1038/nrendo.2009.196

Figure 2.

Figure 2

Gross features, survival and serum FGF23 levels in Kl-knockout mice. Compared with WT mice, Kl−/− mice are smaller in size (a), have markedly elevated serum levels of FGF23 (b) and have a shorter lifespan (around 15–20 weeks) (c). The serum level of FGF23 was measured by enzyme-linked immunosorbent assay using a commercial kit that detects the intact form of FGF23. *P <0.001 versus WT; data presented as mean ± SEM. Abbreviations: Kl−/−, Kl-knockout; WT, wild type.