FIG. 1.

Expression of FPR2/ALX receptor in corneal endothelium. (A) HCE cells cultured as explained in Methods section were proliferated at 7 days, and by 10 days the cells reached confluence. (B) Confluent HCE cells expressed ZO-1, a tight junction-associated protein, showing endothelial cells boundaries in a polygonal pattern. (C) FPR2/ALX receptor is strongly expressed in HCE cells in culture. (D) Human corneal sections showing a strong positive staining for FPR2/ALX in the endothelium. The lower figures in B–D show the nuclei of the cells with 4’, 6-diamidino-2-phenylindole dihydrochloride staining. HCE, human corneal endothelial.