Table 1.

Decrease in Endothelial Cell Damage in Human Corneas Stored in Optisol-GS After Incubation with 15-epi-LXA4

				Endothelial damage
Age	Gender	Postmortem Time (h)	Preservation in wet chamber (h)	Control	15-epi-LXA4	Decrease in damage (%)
32	M	12	43	19±6	8±1.6a	43
35	M	12	23	21±8	10±3.0a	52
52	F	16.5	27.5	14±5	9±3.8a	36
58	F	6	32	23±5.7	11±2.6a	51
65	F	1.5	42.5	18±3.2	10±2.1a	56
88	F	4	44	16±3.8	9±1.8a	44

Pairs of human corneas from the same donor were preincubated in Dulbecco's modified Eagle's medium/F12 media with or without 100 nM 15-epi-LXA4 for 24 h at 37°C, then stored in Optisol-GS with or without 15-epi-LXA4 for 12 days at 4°C. Endothelial cell damage was evaluated by a combination of trypan blue-alizarin red S staining.

^aSignificant differences with regard to control.