Table 4.
Detailed analysis of KEGG hsa:00072 (Synthesis and degradation of ketone bodies)
| Gene Name | Ensembl ID | Feature Count (Total) | Simple Feature§ Count | Simple Feature§ Count p<0.05 | Complex Feature‡ Count | Complex Feature‡ Count p<0.05 | Gene P-value | Other Pathways (path:hsa) |
|---|---|---|---|---|---|---|---|---|
| HMGCS2 | ENSG00000134240 | 12 | 5 | 0 | 7 | 0 | 1 | 00280,00650,00900,01100,03320 |
| HL | ENSG00000117305 | 1 | 0 | 0 | 1 | 1 | < 0.001 | 00280,00650,01100 |
| OXCT2 | ENSG00000198754 | 5 | 2 | 0 | 3 | 0 | 1 | 00280,00650 |
| ACAT1 | ENSG00000075239 | 3 | 0 | 0 | 3 | 1 | 0.114 | 00071,00280,00310,00380,00620, 00640,00650,00900,01100 |
| BDH1 | ENSG00000161267 | 14 | 7 | 0 | 7 | 4 | 0.005 | 00650,01100 |
| BDH2 | ENSG00000164039 | 5 | 1 | 1 | 4 | 2 | < 0.001 | 00650,01100 |
| OXCT1 | ENSG00000083720 | 5 | 2 | 1 | 3 | 2 | 0.001 | 00280,00650 |
| HMGCS1 | ENSG00000112972 | 2 | 1 | 0 | 1 | 0 | 1 | 00280,00650,00900,01100 |
| ACAT2 | ENSG00000120437 | 9 | 6 | 0 | 3 | 1 | 0.211 | 00071,00280,00310,00380,00620, 00640,00650,00900,01100 |
§
a single SNP in an area of LE
‡
an LD block containing two or more typed SNPs