Table 5.
Linear Regression of Final P-Value assigned to a pathway with size and LD biases
No. Features/Pathway | Avg. Feature Size (No. SNPs) | No. Genes/Pathway | ||||
---|---|---|---|---|---|---|
Analysis | Coef | P>t | Coef | P>t | Coef | P>t |
PARIS | 2.52E-05 | 0.093 | −6.70E-06 | 0.382 | 9.10E-04 | 0.126 |
Negative Control | 1.31E-05 | 0.502 | −1.86E-05 | 0.063 | 2.53E-04 | 0.744 |
Biased Negative Control | −1.34E-04 | 0.000 | −4.30E-06 | 0.711 | −5.34E-03 | 0.000 |
Comparison Method | −1.31E-03 | 0.000 | 2.90E-04 | 0.000 | −3.88E-02 | 0.000 |