Table 3.
HLA Ab screened positive samples with 4 or more reactive SABs, by pregnancy
| Screening Cutoff | Total # of LAPS Donors with 4 or more reactive SABs | All Females | Ever Pregnant | 2+ Pregnancies | 3+ Pregnancies | 4+ Pregnancies | |
|---|---|---|---|---|---|---|---|
| N | n (%) of all screen positive LAPS donors using a 3SD cutoff with 4 or more reactive SABs1 | ||||||
| >3SD | Class I | 300 (100%) | 298 (99.3%) | 296 (98.7%) | 279 (93.0%) | 182 (60.7%) | 94 (31.3%) |
| Class II | 241 (100%) | 240 (99.6%) | 236 (97.9%) | 220 (91.3%) | 145 (60.2%) | 72 (29.9%) | |
| >4SD | Class I | 257 (85.7%) | 255 (85.0%) | 253 (84.3% | 237 (79.0%) | 155 (51.7%) | 80 (26.7%) |
| Class II | 237 (98.3%) | 236 (97.9%) | 232 (96.3%) | 216 (89.6%) | 143 (59.3%) | 71 (29.5%) | |
| >5SD | Class I | 138 (46.0%) | 137 (45.7%) | 135 (45.0%) | 129 (43.0%) | 87 (29.0%) | 46 (15.3%) |
| Class II | 231 (95.9%) | 230 (95.4%) | 226 (93.8%) | 212 (88.0%) | 139 (57.7%) | 69 (28.6%) | |
1
Denominator = total number of screen positive (at 3SD) LAPS Donors with 4 or more reactive SABs (n=300 for Class I; n= 241 for Class II).