Table 2.
Characteristics of the 1299 oldest old women in WISE by cognitive status.
| Characteristic (mean (sd) or %) |
Normal N = 767 |
MCI N = 301 |
Dementia N = 231 |
p-valuea |
|---|---|---|---|---|
| Age, Years | 87.8 (2.5) | 88.5 (2.7)d | 89.4 (3.4) d | < 0.001 |
| Education, < High school | 11.5 | 21.3d | 19.5c | < 0.001 |
| Nursing Home Residence | 2.7 | 6.7c | 19.6d | <0.001 |
| History of Stroke | 10.8 | 15.4b | 17.9c | 0.009 |
| Coronary Artery Disease | 19.2 | 18.7 | 20.0 | 0.93 |
| Diabetes | 13.0 | 12.7 | 13.5 | 0.97 |
| Depression | 7.1 | 18.4d | 19.7d | < 0.001 |
| Body Mass Index, kg/m2 | 26.2 (4.5) | 25.7 (4.3) | 25.7 (5.1) | 0.18 |
| APOE e4 allelee | 6.9 | 4.2 | 15.9b | 0.03 |
| APOE e2 allele | 20.1 | 25.0 | 20.6 | 0.69 |
| Previous diagnosis of dementia | 0.1 | 0.7 | 23.9d | <0.001 |
| Taking dementia medication | 1.1 | 3.7c | 20.3d | <0.001 |
| mMMSE | 24.5 (2.0) | 22.1 (3.0)d | 18.4 (5.0) d | <0.001 |
a
P-value by ANOVA across all groups for continuous variables and chi-square for categorical variables
b,c,d
P-value for pairwise comparisons with normal cognitive function is bp<0.05, cp<0.01, dp<0.001
e
Only 309 women were tested for APOE.