Table 3.
Baseline characteristics of patients.
| Characteristic | CVVHDF | SHDF | P value |
|---|---|---|---|
| No. of patients (male/female) | 25 (17/8) | 25 (16/9) | NS |
| Age (years) | 65.3 ± 13.1 | 66.5 ± 12.1 | NS |
| Cause of acute kidney injury (%) | NS | ||
| Nephrogenic | 20 | 24 | |
| Sepsis | 52 | 48 | |
| Cardiogenic | 12 | 12 | |
| Postsurgical | 8 | 8 | |
| Drug induced | 0 | 4 | |
| Hepatic failure | 4 | 4 | |
| Other | 4 | 0 | |
| Presence of CKD on admission (%) | 40 | 44 | NS |
| APACHE II score | 19.6 ± 3.7 | 20.0 ± 4.3 | NS |
| SOFA score | 8.1 ± 2.0 | 8.2 ± 3.2 | NS |
| RIFLE classification | |||
| R (%) | 20 | 20 | NS |
| I (%) | 44 | 40 | NS |
| F (%) | 36 | 40 | NS |
| Mechanically ventilated (%) | 36 | 32 | NS |
| Oliguric (%) | 60 | 60 | NS |
| Baseline systolic blood pressure (mmHg) | 107 ± 32 | 110 ± 29 | NS |
| Required vasopressors (%) | 28 | 24 | NS |
| Renal parameters at RRT initiation | |||
| Serum urea nitrogen (mg/dL) | 69 ± 26 | 68 ± 24 | NS |
| Serum creatinine (mg/dL) | 4.6 ± 2.3 | 4.8 ± 2.1 | NS |
| Days from ICU admission to RRT | 2.1 ± 1.3 | 2.1 ± 1.5 | NS |
APACHE: acute physiology and chronic health evaluation; CKD: chronic kidney disease; CVVHDF: continuous venovenous hemodiafiltration; ICU: intensive care unit; RIFLE: Risk, Injury, and Failure with the outcome classes Loss and End-stage kidney disease classification system; RRT: renal replacement therapy; SOFA: sequential organ failure assessment; SHDF: sustained hemodiafiltration.