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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Cancer Res. 2011 Feb 9;71(7):2445–2454. doi: 10.1158/0008-5472.CAN-10-2628

Figure 4.

Figure 4

IFN-γ is required for M1 macrophage–mediated tumor rejection. Tumor-bearing eyes from C57BL/6, SCID, and IFN-γ KO mice were collected at day 14 and real-time qPCR was used to detect NOS2 (A), F4/80 (B), and CD11b (C). All samples were normalized to GAPDH and compared with non–tumor-bearing eyes in 2 independent experiments. M1- and M2-polarized RAW 264.7 cells served as controls. Mean ± SD. *, P ≤ 0.05.