Table 1.
Arc weight correlation
| Arc Label | Gene Start | Normalized Weight | Gene End | Relation Type |
|---|---|---|---|---|
| 1 | SOS1 | 0.372 | GRB2 | binding |
| 2 | FGF1 | 0.306 | FGFR2 | activation |
| 3 | IL1B | 0.271 | IL1R2 | activation |
| 4 | TRAF2 | 0.241 | FLNA | binding |
| FGF1 | 0.234 | FGFR4 | activation | |
| MAPK4 | 0.204 | PLA2G12B | activation | |
| MAPK8IP1 | 0.202 | MAP4K1 | binding | |
| DUSP4 | 0.188 | MAPK3 | inhibition | |
| MAPK4 | 0.185 | MAP2K1IP1 | binding | |
| DUSP4 | 0.178 | MAPK6 | inhibition | |
| MAPK6 | 0.176 | RPS6KA3 | phosphorylation | |
| MAPK12 | 0.173 | TP53 | phosphorylation | |
| MAP3K7IP1 | 0.092 | MAPK12 | phosphorylation | |
| CASP9 | -0.008 | PAK1 | phosphorylation | |
| CASP7 | -0.123 | MAP4K1 | phosphorylation | |
| RASGRP4 | -0.175 | RRAS2 | activation | |
| MAPK12 | -0.184 | RPS6KA5 | phosphorylation | |
| MAPK1 | -0.191 | YWHAZ | activation | |
| 5 | DUSP4 | -0.199 | MAPK4 | inhibition |
| 6 | PRKACB | -0.209 | RAP1B | activation |
Table shows highly correlated (positive weights) or anti-correlated gene-gene relationships (negative weights) learnt from the model training. The arc label column with numbers 1-6 correspond to the arcs labeled in Figure 3.