. 2011 Mar 3;4:7–14. doi: 10.2147/CCID.S10171

Table 5.

Randomized controlled trials showing the effect of different types of surgery and endovenous therapy on ulcer healing and recurrence

Author	Number randomized	Interventions	Outcome measures	Results
Guest et al⁵⁹	76	Gp1: compression alone Gp2: compression and superficial venous surgery ± perforator surgery	Healing	Gp1: 64% healed Gp2: 68% healed
Zamboni et al⁶⁰	45	Gp1: compression alone Gp2: compression and minimally invasive surgical hemodynamic correction of reflux	Healing and recurrence	Gp1: 96% healed, 38% recurrence Gp2: 100% healed, 9% recurrence
Van Gent et al⁶¹	200	Gp1: compression alone Gp2: compression and subfascial endoscopic perforating vein surgery	Healing and recurrence	Gp1: 73% healed, 23% recurrence Gp2: 83% healed, 22% recurrence
Gohel et al⁶²	500	Gp1: compression alone Gp2: compression and superficial venous surgery	Ulcer healing and ulcer recurrence at 3 years	Gp1: 89% healed, 56% recurrence Gp2: 93% healed, 31% recurrence
Viarengo et al⁶³	52	Gp1: compression alone Gp2: endovenous laser therapy and compression	Healing at 12 months	Gp1: 24% healed Gp2: 82% healed

Abbreviations: Gp1, group 1; Gp2, group 2.