Figure 1.

In left window, dynamic contrast-enhanced ultrasound evaluation of superficial skin melanoma after injection of contrast medium (SonoVue^®) and using perfusion software (Vascular Recognition Imaging, Toshiba, Japan). Quantitative perfusion software (CHI-Q Laboratory, Toshiba, Japan) provides time intensity curve of enhancement (right window). Several perfusion parameters can be extracted after modelling, ie, maximum intensity, slope, area under wash-out, area under wash-in, time to peak, mean transit time.