Table II.
Estimated haplotype frequencies by race/ethnicity.
| ApoCIII
|
Estimated frequency
|
|||||||
|---|---|---|---|---|---|---|---|---|
| − (rs2854117) | −455 T/C (rs2854116) | Intron 1 (466) G/C (rs2070669) | Gly34Gly C/T (rs4520) | Exon 4 SstI 4348(5) C/G (rs5128) | White | Black | Hispanic | |
| 4 | C | C | G | C | C | 0.12 | 0.15 | 0.045 |
| 5 | C | T | C | C | C | 0.016 | 0.049 | — |
| 6 | C | T | C | T | C | 0.030 | 0.033 | — |
| 6 | C | T | C | T | G | — | 0.057 | — |
| 7 | C | T | G | C | C | 0.46 | 0.11 | 0.35 |
| 8 | C | T | G | T | C | 0.10 | 0.063 | 0.18 |
| 9 | T | C | C | C | C | 0.12 | 0.57 | 0.21 |
| 10 | T | C | C | T | C | 0.034 | 0.013 | — |
| 11 | T | C | C | T | G | 0.082 | 0.071 | 0.17 |
| 12 | T | C | G | C | C | 0.017 | — | 0.019 |
| ApoE
|
Estimated frequency
|
||||
|---|---|---|---|---|---|
| Arg112Cys (rs429358) | Arg158Cys (rs7412) | White | Black | Hispanic | |
| 1 | C | C | 0.15 | 0.21 | 0.14 |
| 2 | T | C | 0.78 | 0.71 | 0.83 |
| 3 | T | T | 0.075 | 0.073 | 0.032 |
| EL
|
Estimated frequency
|
|||||
|---|---|---|---|---|---|---|
| rs12970066 | Asn396Ser | rs3829632 (−1309A/G) | White | Black | Hispanic | |
| 1 | A | C | A | 0.49 | 0.74 | 0.46 |
| 2 | A | C | G | 0.013 | — | — |
| 3 | A | G | A | 0.29 | 0.22 | 0.21 |
| 4 | G | C | A | 0.20 | — | 0.33 |
| HL
|
Estimated frequency
|
||||||
|---|---|---|---|---|---|---|---|
| rs2070895 | rs12595191 | rs690 | rs6084 | White | Black | Hispanic | |
| 1 | A | A | T | G | — | — | 0.014 |
| 2 | A | A | T | T | — | 0.012 | 0.022 |
| 3 | A | G | C | G | 0.091 | 0.16 | 0.27 |
| 4 | A | G | C | T | 0.12 | 0.18 | 0.11 |
| 5 | A | G | T | G | 0.017 | 0.045 | 0.049 |
| 6 | A | G | T | T | — | 0.16 | 0.016 |
| 7 | G | A | C | G | 0.057 | 0.012 | 0.035 |
| 8 | G | A | C | T | 0.075 | — | 0.053 |
| 9 | G | A | T | G | — | 0.022 | — |
| 10 | G | G | C | G | 0.17 | 0.085 | 0.13 |
| 11 | G | G | C | T | 0.33 | 0.14 | 0.21 |
| 12 | G | G | T | G | 0.066 | 0.13 | 0.037 |
| 13 | G | G | T | T | 0.060 | 0.058 | 0.049 |
Note: — Indicates estimated frequency < 0.01. Haplotypes with estimated frequencies of less than 0.01 in all three racial/ethnic groups are not presented in this table but are included in the analysis.