Table 3.

Parameters with established importance for assessing disease severity, stability, and prognosis.

Better prognosis	Determinants of prognosis	Worse prognosis
No	Clinical evidence of RV failure	Yes
Slow	Rare of progression of symptoms	Rapid
I, II	WHO functional class	IV
Longer	6-min walking distance	Shorter
Peak oxygen consumption > 15 mL/min/kg	Cardiopulmonary exercise testing	Peak oxygen consumption < 12 mL/min/kg
Normal or near-normal	BNP/NT-pro-BNP plasma levels	Very elevated
No pericardial effusion	Echocardiographic findings	Pericardial effusion
RAP < 8 mmHg and CI ≥ 2.5 L/min/m2	Hemodynamics	RAP > 15 mmHg or CI < 2.0 L/min/m2

RV, right ventricular; BNP/NT-pro-BNP, brain natriuretic peptide/N-terminal fragment of pro-BNP; RAP, right atrial pressure; CI, cardiac index.