Fig. 3.
Amplitude of Dark-Adapted Scotopic and Mesopic and Light-Adapted Photopic ERG Responses in C57Bl/6J and Pttg1−/− Mice. Seven-month old mice were dark-adapted overnight before ERG recording. a Scotopic threshold (log −4.59 cd s/m2 ) and maximum (log −1.01 cd s/m2) responses showed no statistical difference (2 way ANOVA) in rod function comparing knockout and control mice. Mesopic a- and b-wave maximum amplitudes confirmed no statistical difference (2 way ANOVA) in combined rod and cone function. b Pure cone function was also the same in photopic ERG responses (log 2.01 cd s/m2) during 13 min of background illumination (200 cd/m2)