Figure 5.

Region-selective and -specific cells. Region-selective cells fired differently across paths (e.g., EN vs ES), whereas region-specific cells fire differently within paths (e.g., start arm vs goal arm). A, An example of an EN path-selective cell with region-selective (ANOVA, p < 0.05 by region) but not region-specific firing (no region higher than others by Bonferroni-corrected t test). Linearized trial firing diagrams for trials on the EN, ES, WN, and WS paths (top to bottom). The line graph in each shows firing rate across regions with mean rate and 95% confidence intervals plotted as a function of distance along the path. The red line indicates the path selectivity of the cell, whereas the black lines are for nonselective paths. The vertical lines show the approximate positions of behavioral flags [start arm (SA), choice point (CP), goal arm (GA), and reward cup (RE)]. B, An example of WN path-selective cell that is also fired specifically on the SA (Bonferroni-corrected t test, p < 0.05, comparison with other groups). WS is not shown because the cell was recorded during a strategy switch that did not include this path.