Figure 6.

Effects of hyperforin on carrageenan-induced mouse paw edema. (A) Animals (n = 10 for each experimental group) were treated i.p. with 0.25, 1, and 4 mg kg⁻¹ Hyp, 5 mg kg⁻¹ indomethacin, or vehicle (2% DMSO) 30 min before carrageenan subplantar injection. (B) Inhibition of edema formation caused by the treatment with the indicated compounds as percentage of vehicle control calculated from the relative areas under the curves. Data are given as mean ± SE. n = 10, *p < 0.05, **p < 0.01, ***p < 0.001 vs. vehicle (2% DMSO) control, ANOVA + Tukey HSD post hoc tests.