Table 1.

Effect of Hyp on rat carrageenan-induced pleurisy 4 h after i.p. injection.

Treatment	Exudate volume (ml)	Inflammatory cells (×106)	PGE2 (ng/rat)
Vehicle (DMSO)	0.44 ± 0.04	103.0 ± 15.4	1.81 ± 0.16
Hyperforin (4 mg kg−1)	0.16 ± 0.05***	51.3 ± 7.2**	0.97 ± 0.15***
Indomethacin (5 mg kg−1)	0.11 ± 0.04***	35.8 ± 4.2***	0.19 ± 0.05***

Data are given as mean ± SE, n = 10, **p < 0.01, ***p < 0.001 vs. vehicle (DMSO 4%), ANOVA + Tukey HSD post hoc tests.