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. 2011 Jun 3;6(6):e20537. doi: 10.1371/journal.pone.0020537

Figure 2. The expression of Notch ligands and NF-κB is upregulated in KCI mice.

Figure 2

A, The expression of Notch ligands and Notch downstream genes was increased at mRNA level as assessed by Real-time RT-PCR in tumors derived from the KCI mice. B, The expression of Notch ligands and Notch downstream genes was highly expressed in tumors derived from the KCI mice as assessed by western blotting analysis. C, NF-κB p65 activity was increased in tumors derived from the KCI mice by ELISA. D, Left panel, NF-κB p65 DNA-binding activity is increased in tumors derived from the KCI mice as assessed by EMSA. Right panel, phospho-p65 was highly expressed in tumors obtained from the KCI mice as assessed by immunohistochemistry.