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. 2000 May;10(5):659–663. doi: 10.1101/gr.10.5.659

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(a) Alignment of CL-16 and PCLN-1. (Asterisks) Amino acid similarity; (shaded amino acids) highly conserved residues among claudin family members; (TM1–TM4), putative transmembrane domains. (b) Kidney-specific expression of CL-16 in cattle. (Lane 1) Kidney; (lane 2) heart; (lane 3) lung; (lane 4) liver; (lane 5) brain; (lane 6) muscle; (lane 7) kidney; (lane 8) CINF-affected kidney. (Arrow) Position of the 2.9-kb CL-16 transcript. (Bottom) Control glycerol-3-phosphate dehydrogenase expression.

(a) Alignment of CL-16 and PCLN-1. (Asterisks) Amino acid similarity; (shaded amino acids) highly conserved residues among claudin family members; (TM1–TM4), putative transmembrane domains. (b) Kidney-specific expression of CL-16 in cattle. (Lane 1) Kidney; (lane 2) heart; (lane 3) lung; (lane 4) liver; (lane 5) brain; (lane 6) muscle; (lane 7) kidney; (lane 8) CINF-affected kidney. (Arrow) Position of the 2.9-kb CL-16 transcript. (Bottom) Control glycerol-3-phosphate dehydrogenase expression.