Table 4.
Findings at the index endoscopy related to oral use or nonuse of aspirin or NSAIDs
|
1985–1986 |
1995–1996 |
2007–2008 |
Pvalue | |
|---|---|---|---|---|
| n = 99 | n = 108 | n = 99 | ||
| Duodenal ulcer | 52 (53) | 72 (67) | 58 (59) | |
| Gastric ulcer | 47 (47) | 36 (33) | 41 (41) | |
| DU/GU ratio | 1.1 | 2 | 1.4 | NS |
| Aspirin or NSAID users | ||||
| Duodenal ulcer | 12 (23)a | 24 (33)b | 36 (62)c | 0.01–0.06 (a, b vs c) |
| Gastric ulcer | 19 (40) | 18 (50) | 30 (73) | NS |
| DU/GU ratio (users) | 0.6 | 1.3 | 1.2 | |
| Aspirin or NSAID nonusers | ||||
| Duodenal ulcer | 40 (77)a | 48 (67)b | 22 (38)c | 0.03–0.07 (a, b vs c) |
| Gastric ulcer | 28 (60)a | 18 (50)b | 11 (27)c | 0.07 (a vs c) |
| DU/GU ratio (nonusers) | 1.4 | 2.7 | 2 | |
| Ulcer size >2 cm | 23 (23) | 30 (28) | 23 (23) | NS |
| Bleeding activity (Forrest) | ||||
| Arterial (F 1a) | 4 (4) | 5 (5) | 5 (5) | NS |
| Oozing (F 1b) | 15 (15) | 10 (9) | 18 (18) | NS |
| Visible vessel (F 2a) | 2 (2) | 3 (3) | 7 (7) | NS |
| Clot (F 2b) | 9 (9) | 5 (4)b | 16 (16)c | 0.02 (b vs c) |
| Black spot (F 2c) | 2 (2)a | 14 (13)b | 26 (26)c | 0.007–0.0000 (a vs b, c) |
| No signs (F 3) | 67 (68)a | 71 (66)b | 27 (27)c | 0.0006–0.0008 (a, b vs c) |
Abbreviations: DU, duodenal ulcer; GU, gastric ulcer; NSAID, nonsteroidal anti-inflammatory drug.