Figure 5.

Analysis of a portion of the genomes of E. coli and S. typhimurium. The E. coli K12 sequence is from Blattner et al. (1997); the S. typhimurium sequence was obtained from ftp://ftp.sanger.ac.uk/pub/pathogens/st/ST.dbs. (A) A pip of the region. Yellow–green indicates E. coli genes not homologous to S. typhimurium genes. Red indicates an end of a gene in S. typhimurium whose immediate neighbor has its ortholog elsewhere in E. coli. Blue indicates the end of a gene in S. typhimurium whose immediate neighbor has no detectable homolog in E. coli. Gray indicates regions not yet sequenced in S. typhimurium. An overlap between contigs within glyA is colored purple. The capacity to orient gene names vertically is currently not supported by the public server. (B). A closeup showing the region between the glyA and hmpA genes. (C) Textual representation of the pairwise alignment in the intergenic region between glyA and hmpA. Promoters, including the −10 and −35 boxes, and binding sites for PurR and MetR are underlined.