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. 2010 Aug 17;2:101–119. doi: 10.2147/DHPS.S6317

Table 7.

The proportion of RA patients achieving the levels of clinical improvement defined by the ACR (American College of Rheumatology) response criteria with combination golimumab and methotrexate and golimumab monotherapy compared to methotrexate monotherapy

GO-BEFORE28
GO-FORWARD27
MTX + placebo n = 160 Golimumab 100 mg 4 weekly n = 159 MTX + golimumab 50 mg 4 weekly n = 159 MTX + placebo n = 133 Golimumab 100 mg 4 weekly n = 133 MTX + golimumab 50 mg 4 weekly n = 89
At 24 wks (%):
  ACR 20 49 52 62b 28 35 60a
  ACR 50 29 33 40b 14 20 37a
  ACR 70 5 11b 20a

Notes:

a

P < 0.001 compared to placebo group;

b

P < 0.05 compared to placebo group.

Abbreviations: ACR20, ACR50, ACR70, American College of Rheumatology response criteria improvements of 20%, 50%, and 70%; MTX, methotrexate.