Table 1.

Final concentrations of common antibiotic lock solutions

Antibiotic and dosage	Heparin dosage	References
Vancomycin 2 mg/mL	10 units/mL	Robinson et al88
Daptomycin 5 mg/mL	100–10,000 units/mL	Carpenter and Chambers90
Gentamicin 1 mg/mLa	2500 units/mL	Krishnasami et al76
Ciprofloxacin 0.2 mg/dL	5000 units/mL	Droste et al85
Ceftazidime 0.5 mg/dL	100 units/mL	Rijnders et al91
Piperacillin-tazobactam 10 mg/mL	100 units/mL	Del Pozo et al81
Ethanol 70%	No	Onland et al,92 Maiefski et al,93 and Sanders et al94

Note:

^aHeparin partially inhibits the antimicrobial activity of gentamicin, but this inhibition was overcome in vitro by a gentamicin concentration of 1 mg/mL.⁷⁶