Table 2.

Adverse effects of voriconazole

Organ system	Adverse effect
Special senses	Altered light perception Photophobia, blurred vision (<30%)
Cardiovascular system	QTc prolongation
Gastrointestinal disorders	Nausea, vomiting (<5%) Abdominal pain (<10%)
Endocrine system	Adrenal insufficiency (rare)
Liver and biliary system	Increased transaminases (<15%) Hepatitis (rare)
Central nervous system	Hallucinations, confusion (10%) Headache
Skin and appendages	Pruritis, rash (<10%) Photosensitivity (<2%)
Immunologic	Anaphylaxis reported
Maximum tolerated dose in clinical trials	800 mg/day (10 mg/kg/day)

Modified from reference ⁹⁰.