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Schematic representation of lanthanum localization in bone. With micro X-ray fluorescence, lanthanum was found at active bone formation and resorption sites, as well as on quiescent bone surfaces and dispersed throughout the mineralized matrix. Lanthanum concentrations in proximity to resorption lacunae probably reflect lanthanum uptake in osteoclasts or macrophages.58 Adapted with permission from Persy VP et al. Semin Dial. 2006;19(3):195–199.59 Copyright © 2006 Blackwell Publishing.
