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. 2011 Jun 3;6(6):e20412. doi: 10.1371/journal.pone.0020412

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Siamakpour-Reihani et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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2H11 endothelial cells were plated in Matrigel as described in “Material and Methods”. A) SFRP2 induced endothelial tube formation after 6 hours, which was inhibited by tacrolimus in a concentration dependent manner. B) VEGF induced endothelial tube formation after 6 hours, which was inhibited by tacrolimus in a concentration dependent manner.