(A) Slow waves become more local in late sleep. Slow wave involvement (percentage of monitored brain structures expressing each wave) in early NREM sleep versus late NREM sleep in five individuals exhibiting a clear homeostatic decline of SWA during sleep (Figure S1). Error bars denote SEM (n = 1436 and 1698 events in early and late sleep). Asterisk denotes statistically significant difference (p < 2.6 × 10−10, unequal variance t test).
(B) Kcomplexes are more global and similarinearly and latesleep. Same sleep segments and analysisas (A). Error barsdenote SEM (n = 148 and 181 eventsinearly and late sleep; p = 0.98, unequal variance t test).
(C) Spindles become more global in late sleep. Same sleep segments and analysis as (A). Error bars denote SEM (n = 1272 and 2554 events in early and late sleep, p < 0.00014, unequal variance t test).