Fig. 4.

Distribution of the SEA complex proteins across the eukaryota. Representative genomes were searched as described under “Experimental Procedures” and shown as a Coulson plot. Filled sectors represent evidence for orthologues, while open sectors indicate that no orthologue found. Individual taxa are color coded as follows: Opistokhonta, blue; Amoebozoa, light purple; Planta, green; Chromalveolata, orange; Excavata, dark purple. Lower order groupings are indicated, and a key to the factors is given at top. Factors are subdivided into three groups: Sea1, Sea2–4, Npr2, and Npr3. Accession numbers and additional data are listed in the supplemental Table S5.