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. 2011 Feb 27;10(6):M110.006593. doi: 10.1074/mcp.M110.006593

Table IV. Sample sizes required to detect actual fold differences in protein expression as a function of measurement CV (43).

Actual fold-difference
%CV 1.5 2 2.5 3
10 3 3 3 4
20 5 3 3 3
30 10 4 3 3
40 16 6 4 4
50 23 9 6 5
100 68 24 14 11