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. 2011 Mar 29;10(6):M110.007294. doi: 10.1074/mcp.M110.007294

Table IV. Cell-surface N-linked glycoproteins overexpressed in ML2 cells.

Spect-counts Uniq-pep Acc# Gene Name Protein Name Predicted MW (Da) Observed MW (Da) Functions
1 1 P08195 SLC3A2 4F2 cell-surface antigen heavy chain (CD98) 58,023 80,000 Cell growth; amino-acid transport; carbohydrate metabolism
1 1 P49748 ACADVL Very long-chain specific acyl-CoA dehydrogenase 70,745 70,000 Fatty acid metabolism
3 2 O95573 ACSL3 Long-chain-fatty-acid-CoAligase 3 81,338 85,000 Fatty acid metabolism
3 2 Q5T9A4 ATAD3B ATPase family AAA domain-containing protein 3B 73,098 70,000 ATP binding
11 4 P35613 BSG Basigin 42,573 50,000–70,000 Cell surface receptor
5 3 P27797 CALR Calreticulin 48,283 60,000 Molecular calcium binding chaperone
1 1 Q01518 CAP1 Adenylyl cyclase-associated protein 1 52,222 60,000 Cell polarity maintenance; signal trasduction
1 1 Q96A33 CCDC47 Coiled-coil domain-containing protein 47 56,123 65,000 Protein binding
4 2 Q9H5V8 CDCP1 CUB domain-containing protein 1 94,241 130,000 Cell adhesion; tumor progression and metastasis
2 2 P12109 COL6A1 Collagen α-1 (VI) chain 109,602 130,000 Cell adhesion
2 1 A8TX70 COL29A1 Collagen α-5(VI) chain 291,796 120,000 Cell adhesion
1 1 Q15046 KARS Lysyl-tRNA synthetase 68,461 70,000 Protein biosynthesis
1 1 Q9BW27 NUP85 Nuclear pore complex protein Nup85 75,826 75,000 Protein transport; mRNA transport
1 1 Q9NZ01 TECR Synaptic glycoprotein 36,410 300,000 Lipid/steroid biosynthesis
1 1 Q02413 DSG1 Desmoglein-1 114,670 70,000 Cell adhesion
1 1 P06744 GPI Glucose-6-phosphate isomerase 63,335 65,000 Angiogenesis; gluconeogenesis
1 1 A6NKF9 GPR89C Putative protein GPR89C 36,760 300,000 Unknown
1 1 P43304 GPD2 Glycerol-3-phosphate dehydrogenase 81,296 80,000 Calcium ion binding
2 1 A1L0T0 ILVBL Acetolactate synthase-like protein 68,452 70,000 Transferase activity; magnesium ion binding
1 1 Q14721 KCNB1 Potassium voltage-gated channel subfamily B member 1 96,672 60,000 Ion transport
1 1 Q8TF66 LRRC15 Leucine-rich repeat-containing protein 15 65,268 75,000 Protein binding
1 1 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 31,707 80,000 Substrate for protein kinase C; binds calmodulin, actin, and synapsin
2 1 Q7Z434 MAVS Mitochondrial antiviral-signaling protein 57,063 75,000 Innate immune defense against viruses
1 1 Q8NHP6 MOSPD2 Motile sperm domain-containing protein 2 60,051 60,000 Unknown
1 1 Q6PIF6 MYO7B Myosin-VIIb 243,612 250,000 Actin binding motor activity
2 1 O15118 NPC1 Niemann-Pick C1 protein 144,868 250,000 Intracellular trafficking of cholesterol
7 4 Q9UKX7 NUP50 Nucleoporin 50 kDa 50,512 60,000 Protein transport; mRNA transport
1 1 Q6V1P9 DCHS2 Protocadherin-23 323,744 55,000 Cell adhesion
1 1 Q9H307 PNN Pinin 81,679 130,000 Cell adhesion; mRNA processing
8 6 P14923 JUP Junction plakoglobin 82,434 85,000 Junctional plaque formation
1 1 Q15063 POSTN Periostin 93,883 70,000 Cell adhesion
4 3 P18031 PTPN1 Tyrosine-protein phosphatase non-receptor type 1 50,505 55,000 Regulation of insulin signal pathways
8 7 P46060 RANGAP1 RanGTPase-activating protein 1 63,958 80,000 Signal transduction
1 1 Q9GZS1 POLR1E DNA-directed RNA polymerase I subunit RPA49 54,441 55,000 rRNA transcription
3 3 P04843 RPN1 Dolichyl-diphosphooligo-saccharide-protein glycosyltransferase subunit 1 68,641 70,000 N-linked glycosylation
1 1 Q9Y265 RUVBL1 RuvB-like 1 50,538 60,000 Cell cycle; cell division, growth regulation
1 1 Q96QD8 SLC38A2 Sodium-coupled neutral amino acid transporter 2 56,332 300,000 Amino-acid transport
1 1 Q9Y512 SAMM50 Sorting and assembly machinery component 50 homolog 52,342 60,000 Mitochondrial outermembrane translocase complex assembly
3 2 P35498 SCN1A Sodium channel protein type 1 subunit α 230,876 300,000 Ion transport
2 1 O15269 SPTLC1 Serine palmitoyltransferase 1 53,281 50,000 Lipid metabolism
1 1 O00186 STXBP3 Syntaxin-binding protein 3 68,633 70,000 Vesicle docking in exocytosis
7 4 O94826 TOMM70A Mitochondrial import receptor subunit TOM70 68,096 75,000 Receptor for protein import into mitochondria
3 1 Q15849 SLC14A2 Urea transporter, kidney 102,213 70,000 Urea transporter
1 1 P38606 ATP6V1A V-type proton ATPase catalytic subunit A 68,660 70,000 ATP synthesis coupled proton transport