Table 3.
Phenotype Designation Key for Mapped QTLs in Progenies from Hypertensive Rat Strains
| Rat cross | Phenotype description | |
|---|---|---|
| Max DBP | SHR × SKY | maximal diastolic blood pressure |
| Max SBP | SHR × WKY | maximal systolic blood pressure |
| Max MAP | SHR × WKY | maximal mean arterial blood pressure |
| DBP | SHR × WKY | diastolic blood pressure (baseline) |
| SBP | SHR × WKY | systolic blood pressure (baseline) |
| MAP | SHR × WKY | mean arterial blood pressure (baseline) |
| MAP | SHR × DRY | mean arterial blood pressure |
| SBP | FHH × ACI | systolic blood pressure |
| PP | LH × LN | pulse pressure |
| Hs basal MAP | SS × BN | mean arterial blood pressure, arterial catheter implanted, 4 weeks high salt diet (8%) mean of measurements on 3 consecutive days, basal state—lights on and rat asleep |
| Day2 MAP | SS × BN | mean arterial blood pressure, 4 weeks high salt diet (8%), day 2 measurement |
| Baseline BP | SHR × BN | baseline blood pressure average of 30 min on regular diet |
| SBP | LH × LN | systolic blood pressure |
| DBP | LH × LN | diastolic blood pressure |
| MAP | LH × LN | mean arterial blood pressure |
| MAPS | SHR × BN | mean arterial blood pressure average of 30 min after 14 days high salt diet on 1% NaCl |
| SBPS | SHR × BN | systolic blood pressure average of 30 min after 14 days high salt diet on 1% NaCl |
| DBPS | SHR × BN | diastolic blood pressure average of 30 min after 14 days high salt diet on 1% NaCl |
| Salt PP | SHR × BN | pulse pressure average of 30 min after 14 days high salt diet on 1% NaCl |
| ΔSBP | SHR × WKY | systolic blood pressure, change from baseline after ‘startle’ |
| Tail BP | GH × BN | blood pressure measured by sphygomanometer |
| ia BP | GH × BN | intra-arterial blood pressure |
| Δ_wake_m_day2a m_SBP | SS × BN | systolic blood pressure, high salt diet, p.m. active state value minus a.m. basal state |
| Delta_hs_m_ls_MAP | SS × BN | mean arterial pressure, high salt minus low salt, basal state—lights on and rat asleep |
| ΔMAP | SHR × WKY | mean arterial pressure, change from baseline after startle |
| ΔPP% | SHR × WKY | pulse pressure, percent change from baseline after startle |
| ΔSBP% | SHR × WKY | systolic blood pressure, percent change from baseline after startle |
| ΔMAP% | SHR × WKY | mean arterial pressure, percent change from baseline after startle |
| ΔMAP | SHR × BN | delta mean arterial pressure after 14 days (1% NaCl) minus mean arterial pressure on low salt |
| ΔMAP% | SHR × BN | delta mean arterial pressure after 14 days (1% NaCl) minus mean arterial pressure on low salt expressed as percentage |
| ΔSBP% | SHR × BN | delta systolic blood pressure after 14 days (1% NaCl) minus systolic blood pressure on low salt expressed as percentage |
| ΔSBP | SHR × BN | delta systolic blood pressure after 14 days (1% NaCl) minus systolic blood pressure on low salt |
| Delta_wake_m_day2a m_MAP | SS × BN | mean arterial blood pressure, high salt diet, p.m. active state value minus a.m. basal state |
| Delta_hs_m_ls_SBP | SS × BN | systolic blood pressure, high salt minus low salt, basal state—lights on and rat asleep |
| Hs basal SBP | SS × BN | systolic blood pressure, arterial catheter implanted, 4 weeks high salt diet (8%) mean of measurements on three consecutive days, basal state—lights on and rat asleep |
| Hs active MAP | SS × BN | mean arterial pressure, arterial catheter implanted, high salt diet, active state—lights off and rat awake |
| Day1 MAP | SS × BN | mean arterial blood pressure, 4 weeks high salt diet (8%), day 2 measurement |
| Captopril | SHR × BN | mean arterial blood pressure after administration of Captopril |
| Hexamethonium | SHR × BN | mean arterial blood pressure after administration of Captopril and Hexamethonium |